APMAdvances in Precision Medicine2424-85922424-9106WHIOCE PUBLISHING PTE. LTD.10.18063/APM.v11i5.2042ArticleResearch Progress on Risk Factors and Prevention Strategies for Hemorrhagic Transformation After Mechanical Thrombectomy in Acute Ischemic Strokehttps://artdesignp.com/journal/APM/11/5/10.18063/APM.v11i5.2042BaiJiangtao,ZhouLong20261152026-05-26Acute ischemic stroke is characterized by high morbidity, high disability rate, and high mortality, representing a major cerebrovascular disease that jeopardizes national health. Severe stroke caused by large vessel occlusion progresses rapidly, and conventional intravenous thrombolysis has notable limitations. Mechanical thrombectomy can rapidly recanalize the occluded vessel and restore cerebral tissue perfusion. It has now become the principal life-saving treatment for severe acute ischemic stroke, effectively improving patients’ clinical outcomes. However, post-procedural hemorrhagic transformation, as a frequent and devastating serious complication, can substantially offset the therapeutic benefits of the procedure, aggravate neurological impairment, and increase the risks of disability and death. Currently, no unified understanding has been reached regarding the risk factors and pathogenesis of this complication, and standardized and individualized prevention and treatment protocols are still lacking. Therefore, this article explores the relevant research progress on hemorrhagic transformation after mechanical thrombectomy, aiming to provide a reference for clinical risk prevention and control as well as standardized diagnosis and treatment.Acute ischemic stroke,post-mechanical thrombectomy,hemorrhagic transformation,risk factors,prevention and treatment strategies

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