APMAdvances in Precision Medicine2424-85922424-9106WHIOCE PUBLISHING PTE. LTD.10.18063/APM.v11i2.1417ArticleObservation on the Effect of Low Temperature Plasma Therapy on Benign Tumors of Otorhinolaryngologyhttps://artdesignp.com/journal/APM/11/2/10.18063/APM.v11i2.1417ZhengWei20261122026-02-26Objective: To explore the clinical effect and safety of low-temperature plasma in the treatment of benign tumors in different parts of otorhinolaryngology, and to compare the difference between it and traditional surgical methods. Methods: This study is a retrospective study, including 60 patients with benign tumors of otorhinolaryngology from June 2023 to January 2025. According to the operation mode, they were divided into two groups: low temperature plasma group (n=30) and traditional operation group (n=30). The operation time, intraoperative blood loss, postoperative pain score, hospitalization time, complication rate and recurrence rate at one year after operation were compared between the two groups. Results: The intraoperative blood loss, operation time, postoperative pain score and hospitalization time in the low temperature plasma group were significantly better than those in the traditional operation group (P<0.05). There were no serious complications in the two groups, and there was no statistical difference in the recurrence rate one year after operation (P>0.05). Conclusion: Low-temperature plasma therapy is safe and effective in the treatment of benign tumors of otorhinolaryngology, and it has the advantage of minimally invasive, especially for tumors with rich blood supply and lesions in deep anatomical regions.low temperature plasma ablation, Otolaryngology tumor, Benign lesions, minimally invasive surgery

[1] Xu J, 2025, Endoscopic low-temperature plasma radiofrequency ablation hemostasis for epistaxis. Primary Medical Forum, 29(17): 103-105+119. [2] Pang GC, Xu FF, Shen NM, et al., 2025, Effect of low-temperature plasma radiofrequency ablation in endoscopic sinus inverted papilloma. Journal of Harbin Medical University, 59(02): 190-194. [3] Ji BB, Wu JN, 2024, Clinical observation on the early curative effect of low-temperature plasma ablation under nasal endoscope for nasal vestibular cyst. Zhejiang Trauma Surgery, 29(08): 1514-1516. [4] Wu XR, Lu MM, Zhao Y, 2024, Effect of endoscopic sinus surgery assisted with low temperature plasma radiofrequency ablation on nasal function and recurrence rate of patients with inverted papilloma of nasal cavity and paranasal sinuses. Heilongjiang Medical, 48(16): 1936-1939. [5] Duan YF, Fan MJ, 2023, Clinical observation on treatment of maxillary bone cyst with low temperature plasma fenestration under nasal endoscope. Guizhou Medicine, 47(04): 594-595.