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<article xsi:noNamespaceSchemaLocation="http://jats.nlm.nih.gov/publishing/1.1/xsd/JATS-journalpublishing1-mathml3.xsd" dtd-version="1.1" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"><front><journal-meta><journal-id journal-id-type="publisher-id">APM</journal-id><journal-title-group><journal-title>Advances in Precision Medicine</journal-title></journal-title-group><issn>2424-8592</issn><eissn>2424-9106</eissn><publisher><publisher-name>WHIOCE PUBLISHING PTE. LTD.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18063/APM.v11i2.1403</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title>The Application Effect and Clinical Significance of Endoscopic Submucosal Dissection in Early Gastrointestinal Tumors</title><url>https://artdesignp.com/journal/APM/11/2/10.18063/APM.v11i2.1403</url><author>ZhuEnze</author><pub-date pub-type="publication-year"><year>2026</year></pub-date><volume>11</volume><issue>2</issue><history><date date-type="pub"><published-time>2026-02-26</published-time></date></history><abstract>Objective:&amp;nbsp;To analyze the effect and clinical significance of endoscopic submucosal dissection in early gastrointestinal tumors. Methods:&amp;nbsp;74 patients with early-stage digestive tract tumors were selected for data analysis in our hospital from January to December 2024. They were divided into groups using a random number table, with 37 patients in each group. The experimental group was treated with endoscopic submucosal dissection, and the control group was treated with endoscopic submucosal resection. The data between the groups were compared. Results: Compared with the control group, the experimental group had significantly higher en bloc resection rate and complete resection rate, significantly less intraoperative bleeding, significantly shorter hospitalization time, and significantly lower recurrence rate, but the operation time was significantly longer, P&amp;lt;0.05. Comparing the incidence of complications between the two groups, P&amp;gt;0.05. Conclusion: The effect of endoscopic submucosal dissection in early-stage gastrointestinal tumors is ideal. The en bloc resection rate and complete resection rate of patients are significantly higher, the intraoperative blood loss is significantly less, the hospitalization time is significantly shorter, and the recurrence rate is significantly lower. It is worthy of clinical application and promotion.</abstract><keywords>Endoscopic submucosal dissection, early stage, gastrointestinal tumors, application effect, clinical significance</keywords></article-meta></front><body/><back><ref-list><ref id="B1" content-type="article"><label>1</label><element-citation publication-type="journal"><p>[1] Sun HQ, Song C, Zhang J, et al., 2025, Analysis of the Efficacy and Safety of Endoscopic Submucosal Resection, Endoscopic Submucosal Resection and Endoscopic Submucosal Dissection in the Treatment of Upper Gastrointestinal Submucosal Tumors.&amp;nbsp;Journal of Northern Sichuan Medical College, 40(12): 1548-1552.
[2] Zhang WX, Li S, Li ZX, 2025, Complications of Endoscopic Submucosal Dissection for Early-Stage Upper Gastrointestinal Tumors.&amp;nbsp;Journal of Clinical and Pathology, 45(07): 817-823.
[3] Huang ZH, Meng Z, Yang HZ, 2025, Comparative Study of Endoscopic Submucosal Dissection and Traditional Laparotomy in the Treatment of Digestive Tract Tumors.&amp;nbsp;Chinese and Foreign Medical Research, 4(12): 13-15.
[4] Wang LW, Zhu ZM, Zhang ZY, et al., 2024, Retrospective Analysis of Endoscopic Submucosal Dissection in the Treatment of Early Tumors and Precancerous Lesions of the Upper Gastrointestinal Tract.&amp;nbsp;Jilin Medicine, 45(04): 855-859.
[5] Chen JJ, Wang M, 2023, Analysis of the Clinical Efficacy of Microprobe Endoscopic Ultrasound Combined with Endoscopic Submucosal Dissection in the Treatment of Upper Gastrointestinal Submucosal Tumors.&amp;nbsp;Journal of Naval Medicine, 44(08): 822-825.
[6] Xia J, Cao DZ, 2023, Effectiveness and Safety of Endoscopic Mucosal Dissection and Mucosal Resection in the Treatment of Early Gastrointestinal Neuroendocrine Tumors.&amp;nbsp;Hebei Medicine, 45(14): 2172-2174+2178.
[7] Li WF, Xu DB, Chen L, 2023, Efficacy Analysis and Safety Study of Endoscopic Submucosal Dissection in the Clinical Treatment of Patients with Digestive Tract Tumors.&amp;nbsp;Chinese and Foreign Medicine, 42(03): 57-60+65.
[8] Yang F, Yang L, Guo XH, et al., 2023, Clinical Efficacy and Safety of Endoscopic Submucosal Dissection in the Treatment of Gastrointestinal Submucosal Tumors.&amp;nbsp;Henan Medical Research, 32(06): 1082-1084.</p><pub-id pub-id-type="doi"/></element-citation></ref></ref-list></back></article>
