APMAdvances in Precision Medicine2424-85922424-9106WHIOCE PUBLISHING PTE. LTD.10.18063/APM.v11i2.1388ArticleStudy on the Correlation between Serum Homocysteine and Coagulation Function Indicators in Elderly Patients with Hypertensionhttps://artdesignp.com/journal/APM/11/2/10.18063/APM.v11i2.1388LvQiuping20261122026-02-26Objective: To explore the relationship between serum homocysteine (Hcy) levels and coagulation function in elderly patients with hypertension. Methods: 50 elderly patients with hypertension admitted to our hospital from January 2022 to December 2023 were selected as research subjects. According to the patients’ Hcy levels, they were divided into an observation group (high Hcy group, n = 21) and a control group (normal Hcy group, n = 29). Two groups of coagulation function indicators were detected, and the correlation between Hcy and coagulation function indicators was analyzed. Results: The prothrombin time of the observation group was shorter than that of the control group, and the fibrinogen level was higher than that of the control group. The differences were statistically significant (p < 0.05); the Hcy level was positively correlated with fibrinogen and negatively correlated with the prothrombin time. Conclusion: Abnormally elevated Hcy levels in elderly patients with hypertension may affect coagulation function, and the two are closely related. Clinical risk can be assessed by monitoring relevant indicators.Senile hypertension, Serum homocysteine, Coagulation function, Correlation

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